Latest Medical MCQs – Competitive Chemotherapy ( Pharmacology ) MCQs
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Latest Medical MCQs
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Latest Chemotherapy ( Pharmacology ) Mcqs
The most occurred mcqs of Chemotherapy ( Pharmacology ) in past papers. Past papers of Chemotherapy ( Pharmacology ) Mcqs. Past papers of Chemotherapy ( Pharmacology ) Mcqs . Mcqs are the necessary part of any competitive / job related exams. The Mcqs having specific numbers in any written test. It is therefore everyone have to learn / remember the related Chemotherapy ( Pharmacology ) Mcqs. The Important series of Chemotherapy ( Pharmacology ) Mcqs are given below:
Drug chemically related to penicillins is_____________?
A. Sulphonamide
B. Tetracycline
C. Cephalosporin
D. Lincemycin
The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is______________?
A. Erythromycin
B. Ampicillin
C. Penicilling G
D. Methicillin sodium
The drug for choice for treatment of infection involving non-penicillinase producing staphylococcus is___________?
A. Erythromycin
B. Ampicillin
C. Penicilling G
D. Methicillin sodium
The oropharyngeal and oesophageal candidiasis following long-term therapy with a broad spectrum antibiotic can be best treated with____________?
A. Amphotericin
B. Griseofulvin
C. Fluconazole
D. Sulfonates
Antibiotic that interferes with DNA function is_____________?
A. Metronidazole
B. Tetracycline
C. Nystatin
D. Sulphonamides
Which antibiotic is effective against pseudomonas and indole +ve proteus ?
A. Lincomycin
B. Carbenicillin
C. Methicillin
D. Oxacillin
A distinict advantage that tetracyclines have over penicillins is that tetracyclines_____________?
A. Do not cause superinfections
B. Have no side effects
C. Are safer to use during pregnancy
D. Have a wider range of antibacterial activity
Which of the following antibiotics is most frequently associated with pseudomembranous colitis ?
A. Penicillin
B. Ampicillin
C. Clindamycin
D. Cephalosporin
Prolonged administration of streptomycin may result in damage to the____________?
A. Facial nerve
B. Optic nerve
C. Auditory nerve
D. Trigeminal nerve
A patient taking which of the following drug should not eat cheese, etc_____________?
A. Tetracycline
B. Doxycycline
C. Amoxycillin
D. Triamterene
The mechanism of action of chloramphenicol is inhibition of synthesis of_____________?
A. Cell membrane
B. Cell wall
C. Protein
D. DNA
Granesetron, the antiemetic properties because of____________?
A. Gabamimetic actions
B. Dopaminergic receptor – blocking actions
C. Gaba-inhibitory actions
D. Serotonin receptor – blocking action
When broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be____________?
A. Reduced because of increased protein binding
B. Reduced because of enhanced hepatic drug metabolism
C. Increased because of reduction of vitamin sources
D. Increase because of decrease renal excretion of the anticoagulant
Peripheral neuritis is a complication of_______________?
A. Isoniazid
B. Rifampicin
C. Ethambutol
D. Pirazinamide
A patient suffering from syphilis is given pencillin He may develop_____________?
A. Grey Syndrome
B. Cholestatic Jaundice
C. Fanconi Syndrome
D. Jarish – Herxheimer reaction
A child with permanently stained teeth reports, He was most probably administered_____________?
A. Diphenhydramine
B. Disphenyl hydantoin
C. Digoxin
D. Doxycycline
Fluconazole is used for the treatment of______________?
A. Herpes simplex
B. Pemphigus
C. Candidiasis
D. Syphilis
Which of the following penicillins can be given by IV route ?
A. Procaine
B. Benzathine
C. Crystalline
D. Benzathamine
Which drug causes photosensitivity______________?
A. Tetracycline
B. Penicillin
C. Aminoglycoside
D. Cephalosporin
Concurrent administration of tetracyclines is most likely to impair the action of_____________?
A. Chloramphenicol
B. Lincomycin
C. Erythromycin
D. Penicillin
Penicillin is effective against_____________?
A. Neisseria gonorrhoeae
B. Neisseria meningitis
C. Treponema Pallidum
D. All of the above
Which of the following drugs in likely to damage the eighth cranial nerve when administered for a long period of time ?
A. Isoniazid
B. Ethambutol
C. Rifampicin
D. Streptomycin
Pharmacology Miscellaneous MCQs
True about aminoglycoside is all except______________?
A. Are bacteriostatic
B. Excreted unchanged in urine
C. Distributed only extracellularly
D. Teratogenic
Which of the following is a first generation oral cephalosporin_____________?
A. Cefaclor
B. Cefadroxil
C. Cephapirin
D. Cefixime
Best treatment of candidiasis of_____________?
A. Mycostatin
B. Antibiotics
C. Amphoterin
D. None of the above
Cyclosporin is used an______________?
A. Antibiotic
B. Anticancer drug
C. Antiarrythmic
D. Immunosuppresant
Which of the following is a 4th generation cephalosporin______________?
A. Cefaclor
B. Ceftrioxone
C. Cefepime
D. Cefuroxime
Metronidazole______________?
A. Is mainly concentrated in saliva
B. Is used in management of ANUG
C. Has no side-effects
D. Is active against gram-positive aerobes
Cross resistance of isoniazid is seen with_____________?
A. Cycloserine
B. Ethionamide
C. Rifampicin
D. Ethambutol
The oral microblal fiora of a patient on prolonged broad spectrume antibiotic therapy is predominantly____________?
A. Gram positive organism
B. Anaerobic
C. Gram negative organisms
D. Yeast and fungi
True about amoxycillin in comparison to ampicillin is_______________?
A. Higher oral biovailability
B. Equal oral biovailability
C. Lower oral biovailability
D. Can be given Parenterally
An aminoglycoside that is often combined with polymyxin and bacitracin for the treatment of topical infection is____________?
A. Tetracycline
B. Gentamycin
C. Aztreonam
D. Neomycin
Povidine iodine is used for_____________?
A. Tinea
B. Burns
C. Non-specific vaginitis
D. All of the above
B-lactam antibiotics are_____________?
A. Imipenem
B. Penicillin
C. Cephalosporins
D. All of the above
Disseminated candidiasis requires intensive therapy with_____________?
A. Interferons
B. Amphotericin
C. Nystatin
D. Thiobendazole
The administration of penicillin G along with probenicid result in_____________?
A. Increased excretion of probenacid in the feaces and perspiration
B. Increased metabolis of penciling G
C. Increased excretion of probenacid in urine
D. Decreased renal excretion of penciling G
All of the following drugs are components of the MOPP cancer Chemotherapy regimen EXCEPT______________?
A. Vincristine
B. Procarbazine
C. Mechlorethamine
D. Methotrexate
Which one of the following drugs is an antipseudomonal penicillin ?
A. Cloxacillin
B. Cephalexin
C. Piperacillin
D. Dictoxacillin
Cephalosporin active against pseudomonas aeruginosa______________?
A. Cefoperazone
B. Ceftriaxone
C. Cefaclor
D. Cefotaxime
All of the following are topically used sulphonamides except____________?
A. Silversulphadiazine
B. Sulphadiazine
C. Suphacetamide
D. Mafenide
One of the following is not penicillinase susceptible______________?
A. Penicillin G
B. Amoxicillin
C. Piperacillin
D. Cloxacillin
All of the following antibacterial agents acts by inhibiting cell wall systhesis except________________?
A. Monobactams
B. Carbapenems
C. Cephamycins
D. Nitrofurantoins
Nevirapine is a______________?
A. Nucleoside reverse transcriptase inhibitor
B. Protease inhibitor
C. Non-nucleoside reverse transcriptase inhibitor
D. Fusion inhibitor
A diabetic patient developed cellulitis due to Staphylococcus aureus, Which was found to be Methicillin resistant on the antibiotic sensitivity testing. All the following antibiotics will be appropriate except_____________?
A. Teichoplanin
B. Imipenem
C. Vancomycin
D. Linezolid
Which of the following drug does not show renal toxicity_____________?
A. Streptomycin
B. Gentamycin
C. Methoxyprenaline
D. Isoflurane
Topical Antifungal agent in candidiasis is______________?
A. Clotrimazole
B. Ornidazole
C. Clotrimoxazole
D. Propronolol
AIDS is a disease if the immune system primarily affecting_____________?
A. Immunoglobulins
B. Granulocytes
C. Opsonins
D. T lymphocytes
Tetracycline acts on______________?
A. 30S ribosomes
B. Cell membrane
C. 50S ribosomes
D. Inhibiting DNA gyrase
Which of the following can be given as a single dose antimalarial for P.vivax malaria______________?
A. Artemisinin
B. Atovaquone + Proguanil
C. Quinine + Tetracycline
D. Pyrimethamine + Sulfadoxime
All are macrolide antibiotics EXCEPT______________?
A. Roxithromycin
B. Erythromycin
C. Neomycin
D. Calithromycin
Not true about PnG is______________?
A. Very active against sensitive gram positive cocci
B. Destroyed by gastric acid
C. Used for treatment of meningococcal meningitis
D. More concentrated in prostatic secretion and intraocular fluids
The most preferred acute emetic for emesis induced by anticancer drugs is______________?
A. Ondensetron
B. Chlorpromazine
C. Metaclopromide
D. Dicyclomine
The incidence of allergy to penicillin among various population ranges from______________?
A. 1% to 10%
B. 20% to 30
C. 10% to 20%
D. 30% to 40%
While performing a procedure, a resident doctor injures herself with a suture needle that has been used to stitch a patient with HIV infection for 11 years. He has been complaint with therapy for several years and has recently changed tablets because of alteration in his appearance. His last CD4 count was 360 cells/mm. The doctor is offered post exposure prophylaxis. Which regimen should she take ?
A. Ziduvidine and Lamivudine and Stavudine
B. Ziduvidine and Lamivudine and Indivair
C. Ziduvidine and Lamivudine
D. Ziduvidine and Lamivudine and Abacavir
Tetracyclines act by__________________?
A. Inhibiting the binding of aminoacyl tRNA to the ribosomal complex
B. Inactivating elongation factors
C. Inhibiting peptidyl transferase
D. Causing misreading of mRNA
Which of the following is not uridopenicillin ?
A. Mezlocillin
B. Piperacillin
C. Azlocillin
D. Flucloxacillin
Roxithromycin is______________?
A. A long acting macrolide
B. Short acting macrolide
C. Short action quinolone
D. Long acting polypeptide
Not true about piperacilline is_______________?
A. It is a ureido penicillin
B. Inhibits Beta-lactamase
C. Active against pseudomonas aeruginose
D. Given parenterally
A.N.S, Blood And Endocrinal Drugs MCQs
1st generation cephalosporin is________________?
A. Cephadroxil
B. Cefotaxime
C. Cefepime
D. Cefoperazone
Which of the following is beta-lactam antibiotic ?
A. Carbamide
B. Sulphonamide
C. Cephalosporins
D. Ofloxacin
Mechanism of action of beta-lactam antibiotics would be______________?
A. Reduced drug causes strand breaks in DNA
B. Inhibition of cell wall peptidoglycan synthesis by competitive inhibition of transpetidases
C. Inhibition of bacterial protein synthesis by binding to subunit of bacterial ribosomes
D. Inhibition of DNA synthesis by inhibiting DNA-Dependent RNA polymerase
Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT______________?
A. Neomycin
B. Hamycin
C. Streptomycin
D. Gentamicin
Amphotericin B is given for what etiology_______________?
A. Fungal
B. Bacterial
C. Viral
D. Rickettesial
Redman syndrome is side effect of______________?
A. Chloramphenicol
B. Vancomycin
C. Rifampicin
D. Tetracycline
Which among the following anti-HIV drugs is also used to treat viral hepatitis B ?
A. Efavirenz
B. Lamivudine
C. Enfuvirtide
D. Ritonavir
Jerisch-Heximer reaction is treated by administering______________?
A. Tetracyclines
B. Antihistamines
C. Intravenous Penicillin G
D. Steroids
Each of the following statement is correct about metronidazole EXCEPT that it_______________?
A. Active against bacteroides and clostridium
B. is a broad spectrum antiprotozoal drug
C. An effective alternative for infection caused by aerobic gram positive cocci
D. May cause peripheral neuropathy on prolonged use
Colour of teeth stained by tetracycline appear _________ under UV light?
A. Green
B. Red
C. Yellow
D. Brown
IF a bacteria were susceptible to both penicillin and Erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because_______________?
A. Erythromycin exerts its effects extracellularly
B. Penicillin is inactivated by erythromycin
C. Erythromycin enhances the B-lactamases activity
D. Penicillin is only effective against growing cells
Which among the following anti-HIV drugs in an inhibitor of viral fusion ?
A. Enfuvirtide
B. Efavirenz
C. Nelfinavir
D. Etanercept
Which of the most effective for drug asymptomatic amoebic cysts ?
A. Quinidochlor
B. Diloxanide furoate
C. Metronidazole
D. Furazolidone
Which drug can be safely used in lactating mothers ?
A. Chloramphenicol
B. Ampicillin
C. Ciprofloxacin
D. Erythromycin
Which of the following is third generation cephalosporin ?
A. Cefeperazone
B. Cefoxitin
C. Cefuroxime
D. Cefadroxil
Which of the following is associated with neutropenia ?
A. Vinblastin
B. Doxorubicin
C. Cisplastin
D. Methotrexate
Which of the following antibiotics is not used in the treatment of infectious mononucleosis ?
A. Erythromycin
B. Gentamycin
C. Ampicillin
D. Ciprofloxacin
Which of the following is not a broad spectrum antibiotic ?
A. Chloramphenicol
B. Tetracycline
C. Doxycyclin
D. Cephalosporins
INH induced neuropathy is treated with______________?
A. Niacin
B. Pyridoxine
C. Thiamine
D. Riboflavin
The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is_____________?
A. Polypeptide antibiotics
B. Tetracyclines
C. Fluoroquinolones
D. Macrolides
All of the following are therapeutic uses of penicillin G, except_____________?
A. Syphilis
B. Rickettsial infection
C. Bacterial meningitis
D. Anthrax
Clavulanic acid is given in combination with amoxicillin in order to____________?
A. Prolong amoxicillin’s half-life
B. Reduce the risk allergic reactions
C. Reduce the severity of diarrhea
D. Extend amoxicillin’s antibacterial spectrum