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Competitive NSAIDS And other CNS Drugs ( Pharmacology ) MCQs – Medical MCQs

Competitive NSAIDS And other CNS Drugs ( Pharmacology ) MCQs – Medical MCQs

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Latest Medical MCQs

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Latest NSAIDS And other CNS Drugs ( Pharmacology ) Mcqs

The most occurred mcqs of NSAIDS And other CNS Drugs ( Pharmacology ) in past papers. Past papers of NSAIDS And other CNS Drugs ( Pharmacology ) Mcqs. Past papers of NSAIDS And other CNS Drugs ( Pharmacology ) Mcqs . Mcqs are the necessary part of any competitive / job related exams. The Mcqs having specific numbers in any written test. It is therefore everyone have to learn / remember the related NSAIDS And other CNS Drugs ( Pharmacology ) Mcqs. The Important series of NSAIDS And other CNS Drugs ( Pharmacology ) Mcqs are given below:

Quinine is obtained from CINCHONA________________?

A. Leaves
B. Bark
C. Root
D. Seed capsule

Which of the following drugs can be given safely to a patient with renal disease ?

A. Tetracycline
B. Phenacetin
C. Aminoglycoside
D. Diazepam

Thyroid storm can be treated by all the following drugs EXCEPT______________?

A. Dexamethasone
B. Propylthiouracil
C. Propranolol
D. Aspirin

Which among the following Not a pharmacological action of opioids______________?

A. Miosis
B. Anti-emesis
C. Cough suppression
D. Truncal rigidity

Aspirine is useful in all the following conditions EXCEPT_____________?

A. Post myocardial infarction
B. Fever
C. Venous thrombosis
D. Gout

The beneficial effect of drug neostigmine in the treatment of Myasthenia gravis is due to the action____________?

A. It produces more acetycholine receptors
B. It inhibits the action of cholinesterase
C. It is produces more acetylcholine
D. It increases the action of cholinesterase

DOPA and 5-Hydroxytryptophan are clinically important because_____________?

A. They cross blood Brain Barriers
B. They act as neuromodulators
C. They are acidic precursors of Brain amines
D. They are metabolites of various neurogenic amines

Which among the following is a pure antagonist of opioid receptors ?

A. Natrexone
B. Butorphanol
C. Nalbuphine
D. Pentazonice

Which among the following may be used as a sedatives hypnotic ?

A. Zileuton
B. Zolmitriptan
C. Zolpiden
D. Zalcitabine

An anxiolytic, not interacting with GABA ergic system and used in generalized anxiety is______________?

A. Diazepam
B. Alprazolam
C. Buspiron
D. Phenobarbital

Folic acid deficiency occurs in______________?

A. Chloromphenicol
B. Phenytoin
C. Aspirin
D. Cyclosporine

A Hemophiliac patient has rheumatold arthritis. Which drug might be prescribed to relieve the pain ?

A. Acetaminophen
B. Phenylbutazone
C. Acetylsalicylic acid
D. Naproxen

Activation of which of the following receptors would be expected to decrease anxiety_____________?

A. Nicotinic cholinergic receptors
B. Glucocorticoid receptors
C. GABA receptors
D. Glutamate receptors

Which of the following is a muscle relaxant_________________?

A. Hyoscin
B. Pentazocine
C. Scoline
D. Phenylephrine

Ibuprofen is contraindicated in_______________?

A. Patient having bronchitis
B. patients having asthma
C. patients having amoebic dysentery
D. patients having fever

The rate of injection of intravenous Valium is_______________?

A. 1 ml / min
B. 1 mg / min
C. 2.5 ml / min
D. 2.5 mg / min

The muscle relaxant effect of succinylcholine lasts for______________?

A. 2 min
B. 1 min
C. 3-5 min
D. 10 min

Aspirin is contraindicated in______________?

A. Hemorrhage
B. Person suffering form chicken pox or small pox
C. Peptic ulcer
D. All of the above

Which of the following is a short acting barbiturate ?

A. Pentobarbital
B. Secobarbital
C. Diazepam
D. Phenobarbita

Gastric irritation is minimum with one of the following non-steroidal anti inflammatory drugs_____________?

A. Tenoxicam
B. Piroxicam
C. Meloxicam
D. Indomethacin

The anti-inflammatory analgesic drug the causes least gastrointestinal symptoms is______________?

A. Phenyl butazone
B. Aspirin
C. Paracetamol
D. Indomethacin

Paracetamol is contraindicated in_______________?

A. Chronic hepatitis
B. Nephritis
C. Bleeding disorders
D. A & B

Which of the following drugs is currently widely used in treating opioid dependent individuals?

A. Alphaprodine
B. Methadone
C. codeine
D. Pentazocine

Birbiturates in pediatrics is_____________?

A. Can be used safely
B. Low safety
C. Contraindicated
D. Not much use

A patient with grand mal epilepsy would likely be under treatment with_____________?

A. Meprobamate
B. Trimethadione
C. Pentobarbital
D. Phenytoin

Drugs Acting On CVS, GIT And Respiratory System MCQs

The Ethyl alcohol (Ethanol) is more effective when mixed with water and used as_____________?

A. 20 to 30 percent
B. 10 to 20 percent
C. 40 to 50 percent
D. 60 to 70 percent

Best and most effective drug to control convulsions in toxicity cases is______________?

A. Phenytoin
B. Phenobarbitone
C. Diazepam
D. Carbemezipine

Which of the following drugs causes extra pyramidal symptoms_____________?

A. Salicylates
B. Antibiotics
C. Barbiturates
D. Phenothiazines

Phenytoin is associated with_____________?

A. Folic acid deficiency
B. Cushing’s syndrome
C. Alzhiemer’s disease
D. Vitamin C deficiency

All of the following statements about opioids is correct except_____________?

A. Ethomorphine is similar to pethidine chemically
B. Pentazocine shows withdrawal symptoms in opioid dependent patients
C. Partial agonists are free from classic opioid adverse effects
D. Pentazocine and buprinorphine

All of the following decrease skeletal muscle tone by CNS effects except____________?

A. D-tubocurarin
B. Beclofen
C. Diazepam
D. Mephensin

Amitryptyline is a____________?

A. Sedative
B. Antibiotic
C. Tricyclic antidepressant
D. Diuretic

Thiopentone action is terminated by______________?

A. Metabolism
B. Excretion
C. Redistribution
D. Recycling

Phenothiazines are used to____________?

A. Suppress coughing
B. Alter psychotic behaviour
C. Produce muscle relaxation
D. Produce analgesia

Drug that does not cause sedation________________?

A. Buspirone
B. Zopiclone
C. Nitrazepam
D. Diazepam

Drug which is used to control status epilepticus is______________?

A. Diazepam
B. Glyceryl trinitrite
C. Sodium nitroprusside
D. Pheno barbital

Prolonged use of aspirin leads to______________?

A. Bleeding defects
B. peptic ulcer
C. Carcinoma
D. A & B

Aspirin causes___________?

A. Hemolytic anemia
B. Agranulocytosis
C. Aplastic anemia
D. Hypoprothrombinemia

Clotting time is most like to be prolonged by the administration of____________?

A. Barbiturates
B. Vitamin K
C. Acetominophen
D. Acetyl salicylic acid

Aspirin is used in treatment of Myocardial Infarction___________?

A. It inhibits thromboxanes
B. It is a vasodilator
C. It stimulates Prostacyclins
D. Ithelps in reducing inflammatory aggregate

Antagonist of morphine is_______________?

A. Naloxone
B. Nalpuphine
C. Nalosphine
D. Methadine

Which of the following opioids is not given intrathecally ?

A. Remifentanil
B. Sufentanil
C. Morphine
D. Fentanyl

All of the following statements about pain are correct except_____________?

A. Dysphoria is associated with S receptors
B. Analgesia is associated with μ and k receptors
C. NSAIDS benefit by preventing prostaglandin synthesis
D. Naloxane is a non-competitive antagonist and irreversibly opposes the opioids

Aspirin is avoided in children with influenza infection because of association______________?

A. Reye’s syndrome
B. Diarrhoea
C. Nausea
D. Acid-base imbalance

The most prominent toxic effect associated with acetominophen use is______________?

A. Haemorrhage
B. Respiratory alkalosis
C. Hepatic necrosis
D. Gastric Ulceration

An attack of bronchial asthma is most likely to be triggered by________________?

A. Ibuprufen
B. Aspirin
C. Diclofenac potassium
D. Mefenamic acid
E. Both A & B

Narcotic overdose can be antagonized by______________?

A. Atropine
B. Diphenhydramine
C. Naloxane
D. Nalorphine

Neusea and vomiting that are associated with administration of opioid analgesic is the result of stimulation of the_____________?

A. Emetic system
B. Limbic system
C. Chemoreceptor trigger zone (CTZ)
D. Opioid receptors in G.I.T

Verril’s sign is seen in_________________?

A. Diazepam administration
B. Paget’s disease
C. Digitalis toxicity
D. Unconscious states

A common side effect associated with all NSAID drugs is_______________?

A. Xerostomia
B. Gastric irritation
C. Drowsiness
D. Constipation

A paralyzing dose of succinylcholine initially elicits______________?

A. CNS depression
B. Muscle fasciculation
C. CNS stimulation
D. Decreased salivation

Aspirin produces all of the following effects except_____________?

A. Prolonged prothrombin time
B. Frank gastric bleeding
C. Platelet dysfunction
D. Constipation

Chemotherapy MCQs

All are true of diazapenes except____________?

A. Clonazeppam is used in the treatment of petitmal epilepsy
B. Benzodiazepam is used in the long term treatment of psychic disorders
C. Benzodiazepam is used in treatment of status epilepticus
D. None of the above

Shortest acting opioid analgesic is______________?

A. Fentanyl
B. Morphine
C. Remifentanil
D. Sufentanil

Aspirine cause_____________?

A. Increase BT
B. Increase PTT
C. Increase CT
D. Increase APTT

True about use of midazolam over diazepam is sedation in all except ?

A. Less thrombophlebitis due to low solubility in blond
B. More potent than diazepam
C. More plasma binding and less toxicity
D. Binds to benzodiazepine receptors with 3-4 time more avidly

All NSAIDs block cycloxygenase and____________?

A. Prostaglandin synthesis
B. Preglandin synthesis
C. Ectoglandin synthesis
D. Costaglandin synthesis

Following analgesic combination should be avoided ?

A. Ibuprofen and Paracetamol
B. Paracetamol and Dextropropoxyphene
C. Aspirin and Codeine
D. Ibuprofen and DIclofenac

Which of the following drug induces parkinsonism ?

A. Chloroquine
B. Chlorpromazine
C. Chlorpheniramine
D. Chlorhexidine

Which one of the following NSAIDs has adverse effects on liver ?

A. Acetaminophen
B. Ibuprofen
C. Aspirin
D. Diclofenac Sodium

Atypical Antipsychotic are all except______________?

A. Clozapine
B. Olanzepine
C. Risperidone
D. Thioridazone

Benzodiazepine antagonist is________________?

A. Flumazenil
B. Naloxone
C. Furazolidone
D. Naltrexone

Which one of the following is NOT an ergot alkaloids_____________?

A. Lysergic acid diethylamide (LSD)
B. Bromocriptine
C. Ketanserin
D. Methysergide

BEnzodiazepines are true in___________________?

A. After metabolism of other drugs in liver
B. More safe than other sedatives when take in larger amounts
C. Produce distortion in sleep more than other sedatives
D. All have metabolically active substrates

Which of the following is true about parasympathetic nervous system ?

A. Ach is transmitter at both pre & post synaptic junction
B. Post ganglionic fibres are longer than pre ganglionic fibres
C. It causes dilatation of skeletal muscles
D. Noradrenalin is the neurotransmitter at post ganglionic junction

Drugs like barbiturates precipitate symptoms of prophyria because______________?

A. They depress ALA synthase
B. They induce heme oxygenase
C. They inhibit ALA synthase
D. They inhibit heme oxygenase

The statement Not true of Selective Cox – 2 inhibitor is________________?

A. The analgesic and anti-inflammatory effects identical to that of Non-selective NSAID
B. Fewer incidence of gastrointestinal side effect
C. Safe in patients with renal insufficiency
D. They do not offer the cardio protective effect

Which one of the following muscle relaxant has the maximum duration of action ?

A. Vecuronium
B. Atracurium
C. Rocuronium
D. Doxacurium

All are symptoms of opiate withdrawls except______________?

A. Lacrimation
B. Diarrhea
C. Mydriasis
D. Excessive speech

Buprenorphine acts by following mechanism________________?

A. Kappa receptor antagonist
B. Mu receptor antagonist
C. Mu receptor partial agnoist
D. Kappa receptor partial agonist

A patient with grandmal epilepsy would likely be under treatment with_______________?

A. Pentobarbital
B. Meprobamate
C. Trimethadione
D. Phenytoin

Respiratory depression is seen with_____________?

A. Non-barbiturates
B. Tranquilizers
C. Synthetic narcotics
D. Antidepressants

The first choice of drug for patitmal seizure is________________?

A. Carbamazepine
B. Phentoin sodium
C. Phenobarbitone
D. None of the above

An untoward effect of that is common to all phenothiazines is______________?

A. Suppression of prolacin
B. Rigidity and tremor at rest, particularly with prolonged use
C. A marked increase in blood pressure
D. Nausea

Platelet aggregation in inhibited by all except_______________?

A. Salicylates
B. Indomenthacin
C. Dypyradimole
D. Phenobarbitone

Salicylate administration is contraindicated in pregnancy because_______________?

A. Causes pulmonary hypertension of newborn
B. It delay onset of labour
C. Readily croses placental barrier
D. All of these

Which of the following is a non steroidal anti inflammatory agent with a tendency to produce blood dyscrasias ?

A. Ibuprofen
B. Aspirin
C. Indomethacin
D. B & C

The principle central action of caffeine is on the________________?

A. Cerebral cortex
B. Hypothalamus
C. Corpus callosum
D. Spinal cord

An antiepileptic drug used in petitmal epilepsy is______________?

A. Dilantoin sodium
B. Phenobarbitonse
C. Diazepam
D. Ethosuximide

NSAID which undergoes enterohepatic circulation______________?

A. Aspirin
B. Piroxicam
C. Phenylbutazone
D. Ibuprofen

Acute Barbiturate poisoning results in_______________?

A. Liver failure
B. Renal failure
C. Respiratory failure
D. Convulsions

One of the obious consequences of alchol ( ethenol), ingestion in many individual is facial flushing and increased heart rate triggered off by alcohol getting metabolized to______________?

A. Propanaldehyde
B. Acetaldehyde
C. Formaldehyde
D. Butanaldehyde

A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?

A. Isoniazide
B. Rifampicin
C. Pyrazamide
D. Ethambutol

Carbamazepine is a type of___________?

A. Antidepressant
B. Antibiotic
C. Antinflammatory
D. Antiemetic

Morphine a powerful opioid analgesic drug should be avoided in all the following conditions except____________?

A. Constipation
B. Bronchial asthma
C. Left ventricular failure
D. A & C

An attack of migraine can be easily terminated by___________?

A. Morphine
B. Ergotamine
C. Acetylcholine
D. Ibuprofen

One of the benzodiazepines (BDZ) comparatively safe in pregnancy is (Category-B) ?

A. Zolpidem
B. Alprozolam
C. Lorazepam
D. None of the above

Miscellaneous MCQs

Drug which causes gingival hyperplasia_____________?

A. Cyclosporin
B. Erythromycin
C. Nifedipine
D. Aspirin
E. Both A & C

The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except________________?

A. Bradycardia
B. Decreased sweating
C. Decreased salivation
D. Mydriasis

IV ultrashort acting barbiturate_____________?

A. Pentobarbitone
B. Meprobamate
C. Thiopentone
D. Phenobarbitone

Aspirin acts on which part of brain ?

A. Substantia gelatinosa
B. Medulla
C. Limbic system
D. Cortex

NSAID’s have adverse effect on________________?

A. Kidney
B. Bone
C. Liver
D. Stomach

Which of the following drug is used to counter act the gastric irritation produced by administration of NSAID_______________?

A. Pirenzipine
B. Roxatidine
C. Betaxolol
D. Misoprostol

Prolonged use of aspirin causes_______________?

A. Hypoprothrombinemia
B. Hyprphosphatasia
C. Hyperprothrombinemia
D. Hypercalcemia

Salicylate overdose in children causes_______________?

A. Kernicterus
B. Rye’s syndrome
C. Crystalluria
D. None of the above

A patient on 300 mg of aspirin will show all the following except________________?

A. Irreversible inhibition of cyclooxygenase path way
B. Inhibition of thromboxane TXA2
C. Prolonged bleeding time
D. Inhibition of prostaglandin PGI2

Which of the following anti inflammatory drug is a COX-2 inhibitor_____________?

A. Ketoprofen
B. Aspirin
C. Rofecoxib
D. Sulidec

Pregnant patient can be safely given______________?

A. Metronidazole
B. Paracetamol
C. Tetracycline
D. Barbiturates

Aspirin is contraindicated in_______________?

A. Angina
C. Peptic ulcer
D. Hypertension

Less gastrointestinal bleed is seen in the following NSAID_______________?

A. Naproxen
B. Meloxicam
C. C0X2 specific inhibitors
D. Ibuprofen

Which of the following anti-epileptic agents causes the reversible side-effect of gingival hyperplasia ?

A. Phenobarbitone
B. Ethosuximide
C. Sodium valporate
D. None of the above

Amyl nitrate is most commonly administered _________________?

A. By inhalation
B. Intravenously
C. Sub lingually
D. Orally

Which of the following is a nonsteroldad anti inflammatory agent with a tendency to produce blood dyscriasis ?

A. Indomathecin (indocin)
B. Ketoroloc
C. Ibuprofen (Motrin)
D. Aceteminophen

Which of the following is an irreversible side enact resulting from long term administration of phenothiazline antipsychotics__________________?

A. Infertility
B. Tardive dyskinesia
C. Parkinsonism
D. B & C

Which of the following can be given safely to a patient of congestive heart failure________________?

A. Diclofenac sodium
B. Paracetamol
C. Aspirin
D. Ibuprofen

Which of the following is not a contraindication in the therapy with opioids_____________?

A. use in impaired pulmonary function
B. Use in head injury patient
C. Use of agonist with mixed agonist-antagonist
D. Use in severe constant pain

Morphine is contraindicated in all of the following except_______________?

A. Pulmonary oedema
B. Bronchial asthma
C. Emphysema
D. Head injury

Which of the following drugs is least efficacious in the treatment of cemporal lobe epilepsy ?

A. Phenytoin sodium
B. Phenobarbitone
C. Primidone
D. Carbamazepine

Competitive NSAIDS And other CNS Drugs ( Pharmacology ) MCQs – Medical MCQs